The band's iconic 1984 concert film Stop Making Sense will be released in IMAX on September 22 and other theaters on September 29.
While there is no promise of an on-stage reunion, Byrne and his former bandmates are expected to promote the film in the coming weeks.
And reflecting on Talking Heads' 1992 demise, Byrne tells People: "As a younger person, I was not as pleasant to be around. When I was working on some Talking Heads shows, I was more of a little tyrant.
"And then I learned to relax, and I also learned that collaborating with people, both sides get more if there’s a good relationship instead of me telling everybody what to do.
“I think the end wasn’t handled well. It was kind of ugly.
"I have regrets on how that was handled. I don’t think I did it in the best way, but I think it was kind of inevitable that would happen anyway.
"We have a cordial relationship now. We’re sort of in touch, but we don’t hang out together."
The 40th anniversary of Talking Heads' collaboration with film director Jonathan Demme is to be celebrated with a newly restored 4K version of the film that will return to cinemas for a global theatrical run, and a deluxe version of the soundtrack that will include the complete concert for the first time.
The deluxe edition of Stop Making Sense will be available through Rhino on August 18 as a limited edition, two LP set and digitally along with a Dolby Atmos mix of the complete concert, mixed by Jerry Harrison and E.T. Thorngren, who also mixed the original release.